ABSTRACT
Management of sedation and analgesia in critical care medicine is a multidisciplinary
process that involves physicians, nurses, pharmacists, and other healthcare providers.
Optimal management of these common issues includes recognition of the importance of
predisposing and causative conditions that contribute to the sensations of pain and
discomfort, anxiety, and delirium. Treatment includes pharmacological intervention,
correction of predisposing factors, and use of other preventative and nonpharmacological
measures. It is increasingly clear that, although necessary for patient comfort, sedative
and analgesic medications can have adverse consequences, including side-effects as
well as prolonged mechanical ventilation and ICU length of stay. Optimal use of sedative
and analgesic medications involves matching unique properties of specific medications
with individual patient characteristics. Guidelines that minimize unnecessary variability
in practice, prevent excessive medication, and emphasize management based on individual
patient characteristics improve the effective utilization of these medications.
KEYWORD
Sedation - analgesia - guidelines